D обнаружена у дзёмонцев, тезисы одного из докладов на SMBE 2018:
POB-162 Phenotype and phylogeny of Neolithic Japanese hunter-gatherers, Jomon people, based on whole nuclear genome sequences
Hideaki Kanzawa-Kiriyama 1 , Timothy Jinam 2, Yoshuke Kawai 3, Takehiro Sato 4, Kazuyoshi Hosomichi 4, Atsushi Tajima 4, Kryukov Kirill 5, Noboru Adachi 6, Naruya Saitou 2, 7, Ken-ichi Shinoda 1
1 National Museum of Nature and Science (Japan),
2 National Institute of Genetics (Japan),
3 University of Tokyo (Japan),
4 Kanzawa University (Japan),
5 Tokai University (Japan),
6 University of Yamanashi (Japan),
7 Graduate University fo Advanced Studies (SOKENDAI) (Japan)
Funadomari Jomon are 3,500-3,800 year-old northern Japanese hunter-gatherer. Here, we determined high depth and low depth nuclear genome sequences from Funadomari Jomon female (F23) and male (F5). F5 belongs to Y chromosome haplogroup D1b2b, which is rare haplogroup in modern Japanese. We genotyped the genome of F23, and HLA class-I type (homozygous for A*24:02:01, B*15:01:01, and C*03:03:01) and many phenotypic traits (e.g. non-shovel shape incisor and wet-type earwax) were determined. We observed high HBD similar to modern southern Native Americans, but long HBD tracts longer than 10cM is small, suggesting no close consanguineous mating but small population size in northern Jomon populations. MSMC analysis also suggested their small population size for more than 10,000 years. Phylogenetic relationship between F23 and modern/ancient Eurasians and Native Americans showed a deep divergence of F23 in East Eurasia, probably before the split of the ancestor of Native Americans from East Eurasians, but after the split of 40,000-year-old Tianyuan. This indicates that Northern Jomon people are genetically isolated from continental East Eurasians for long time. Intriguingly, we found that not only modern three Japanese (Ainu, mainland Japanese, and Ryukyuan) but also Ulchi, Koreans, the aboriginal Taiwanese and the Philippines are genetically closer to F23 compared to Han Chinese at the significant level (Z>3). These informations are one of a key to reconstruct ancient population structure and history in East Eurasia.