Y-chromosomal DNA analysis in French male lineages

[Centurion]

Y-chromosomal DNA analysis in French male lineages // Forensic Science International: Genetics, Received 29 July 2013; received in revised form 16 December 2013; accepted 18 December 2013. published online 31 December 2013

E. Ramos-Luis et al.

French population, despite of its crucial geographic location for repopulation movements of Europe across time, it has been insufficiently characterized at the genetic level, especially for Y-chromosomal DNA variation. In order to make a genetic structure characterization, we have analysed the Y-chromosome diversity of 558 male individuals, scattered along 7 different French regions: Alsace (Strasbourg), Auvergne (Clermont-Ferrand), Bretagne (Rennes), Île-de-France (Paris), Midi-Pyrénées (Toulouse), Nord-Pas-de-Calais (Lille) and Provence-Alpes-Côte d’Azur (Marseille). A total of 17 Y-chromosome STRs and 27 Y-chromosome SNPs were genotyped for each individual. Even though we find that most of the individual populations in France were not differentiated from each other, Bretagne population shows population substructure, an important fact to be considered when establishing general population databases.

http://www.fsigenetics.com/article/S1872-4973(13)00255-X/abstract

[сармат]

Y-chromosomal DNA analysis in French male lineages

E. Ramos-Luise , A. Blanco-Verea , M. Brión , V. Van Huffel , P. Sánchez-Diz ,A. Carracedo

Abstract

French population, despite of its crucial geographic location for repopulation movements of Europe across time, it has been insufficiently characterized at the genetic level, especially for Y-chromosomal DNA variation. In order to make a genetic structure characterization, we have analysed the Y-chromosome diversity of 558 male individuals, scattered along 7 different French regions: Alsace (Strasbourg), Auvergne (Clermont-Ferrand), Bretagne (Rennes), Île-de-France (Paris), Midi-Pyrénées (Toulouse), Nord-Pas-de-Calais (Lille) and Provence-Alpes-Côte d’Azur (Marseille). A total of 17 Y-chromosome STRs and 27 Y-chromosome SNPs were genotyped for each individual. Even though we find that most of the individual populations in France were not differentiated from each other, Bretagne population shows population substructure, an important fact to be considered when establishing general population databases.


Figure 1. Haplogroup frequencies distribution in France. Alsace (ALS, N=81), Auvergne (AUV, N=89), Bretagne (BRT, N=115), Île-de-France (IDF, N=91), Midi-Pyrénées (MPY, N=67), Nord-Pas-de-Calais (NPC, N=70) and Provence-Alpes-Côte d’Azur (PAA, N=45).

http://www.fsigenetics.com/article/S1872-4...0255-X/fulltext

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