Генетика коренного населения российского Дальнего Востока:
O–PSM–14
Gene geography of the Russian Far East populations – faces, genome-wide profiles, and Y-chromosomes
O. Balanovsky1,2,3, Y. Bogunov1,2, E. Lukyanova1, A. Agdzhoyan1,2, V. Zaporozhchenko1,2, M. Zhabagin4, A. Maurer5E. Balanovska1,2,3
Russian Far East is not only a remote area of Eurasia but also a link of the chain of Pacific coast regions, spanning from East Asia to Americas, and many prehistoric migrations are known along this chain. The Russian Far East is populated by numerous indigenous groups, speaking Tungusic, Turkic, Chukotko-Kamchatka, Eskimo-Aleut, and isolated languages. This linguistic and geographic variation opens question about the patterns of genetic variation in the region, which was significantly undersampled and received minor attention in the genetic literature to date. To fill in this gap we sampled Aleuts, Evenks, Evens, Itelmens, Kamchadals, Koryaks, Nanais, Negidals, Nivkhs, Orochi, Udegeis, Ulchi, and Yakuts. We also collected the demographic information of local populations, took physical anthropological photos, and measured the skin color. The photos resulted in the "synthetic portraits" of many studied groups, visualizing the main features of their faces.
We genotyped 150 samples using the Illumina genome-wide SNP panels: 730k OmniExpress chip and the largest commercially available 4M Omni5Exome-4 chip.
This dataset revealed the contrast between gene pools of populations from Amur basin, Chukotka-Kamchatka speakers, and Evenks/Evens. The Chukotka-Kamchatka populations are genetically very specific comparing with all other Eurasian groups. They demonstrated weak signals of similarity with Amerinds and might carry a portion of the Upper Paleolithic Beringian ancestry. The other Russian Far East groups carry mainly the Amur basin/Central Asian genetic component, traced back till the Neolithic aDNA samples from the Amur region, but also East Asian and North Siberian components.
We also analyzed ~1,000 Y-chromosomes from the same indigenous groups. The subset was sequenced, resulting in the detailed phylogenetic tree with many newly revealed branches. The remained samples were genotyped by Y-SNPs, including those defining the new branches. The Y-chromosomal data confirmed the genetic peculiarity of the Asian north-easternmost populations. We also demonstrated that gene pool structure corresponds with the clan structure, and clans within the same group might have different origin.
To conclude, we performed the molecular anthropological and physical anthropological study of the Russian Far East revealing the complex and ancient gene pools which are structured not only by geography, but also by language and clans.
Геномы охотников-собирателей и земледельцев из Северо-Восточного Китая:
O–PSM–15
Genomic insight into the Neolithic transition peopling of Northeast Asia
C. Ning1
East Asian representing a large geographic region where around one fifth of the world populations live, has been an interesting place for population genetic studies. In contrast to Western Eurasia, East Asia has so far received little attention despite agriculture here evolved differently from elsewhere around the globe. To date, only very limited genomic studies from East Asia had been published, the genetic history of East Asia is still largely unknown. In this study, we shotgun sequenced six hunter-gatherer individuals from Houtaomuga site in Jilin, Northeast China, dated from 12000 to 2300 BP and, 3 farming individuals from Banlashan site in Liaoning, Northeast China, dated around 5300 BP. We find a high level of genetic continuity within northeast Asia Amur River Basin as far back to 12000 BP, a region where populations are speaking Tungusic languages. We also find our Compared with Houtaomuga hunter-gatherers, the Neolithic farming population harbors a larger proportion of ancestry from Houtaomuga related hunter-gathers as well as genetic ancestry from central or perhaps southern China. Our finding further suggests that the introduction of farming technology into Northeast Asia was probably introduced through demic diffusion.
Геномы из Монголии бронзового века: O–MOB–03
Bronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe
C. Warinner1, C. Jeong1, S. Wilkin1, T. Amgalantugs1, A. Bouwman1, W. Taylor1, R. Hagan1, S. Bromage1, S. Tsolmon1C. Trachsel1, J. Grossmann1, J. Littleton1, C. Makarewicz1, J. Krigbaum1, M. Burri1, A. Scott1, G. Davaasambuu1, J. Wright1F. Irmer1, E. Myagmar1, N. Boivin1, M. Robbeets1, F. Rühli1, J. Krause1, B. Frohlich1, J. Hendy1
Recent paleogenomic studies have shown that migrations of Western steppe herders (WSH), beginning in the Eneolithic (ca. 3300-2700 BCE), profoundly transformed the genes and cultures of Europe and Central Asia. Compared to Europe, the eastern extent of this WSH expansion is not well defined. Here we present genomic and proteomic data from 22 directly dated Bronze Age khirigsuur burials from Khövsgöl, Mongolia (ca. 1380-975 BCE). Only one individual showed evidence of WSH ancestry, despite the presence of WSH populations in the nearby Altai-Sayan region for more than a millennium. At the same time, LC-MS/MS analysis of dental calculus provides direct protein evidence of milk consumption from Western domesticated livestock in 7 of 9 individuals. Our results show that dairy pastoralism was adopted by Bronze Age Mongolians despite minimal genetic exchange with Western steppe herders.