Polako/Davidski Eurogenes plots

[Srkz]

А есть какой-то график наглядный?
Ну вроде по каждому состав и добавить для сравнения русских, финнов, немцев, китайцев, индейцев и т.д.

Вот таблица от калькулятора Поляко, добавил свежие данные из текстового файла в конец (там кое-что будет дублироваться из-за этого)

[Eugene]

Спасибо Сергей!
Видимо при сравнени дДНк и современных за давностью нельзя использовать много компонент. Получилось слишком разные все.

[Srkz]

Спасибо Сергей!
Видимо при сравнени дДНк и современных за давностью нельзя использовать много компонент. Получилось слишком разные все.

Там низкое качество генотипирования, видимо, это сильно добавляет шума. Но в целом тенденция прослеживается. North Sea, Baltic и Eastern Euro это охотники-собиратели. West med и West Asian - вклад земледельцев. Atlantic - переходный компонент, общий для земледельцев и охотников. Amerindian, South Asian объединяют с мальтинцем (наряду с Eastern Euro). Oceanian вообще непонятно откуда, то ли шум, то ли недифференцированность, то ли еще какие-то особенности алгоритма 

[FenriR]

Спасибо Сергей!
Видимо при сравнени дДНк и современных за давностью нельзя использовать много компонент. Получилось слишком разные все.

помимо укзанного ув. Srkz, сэмплы, порой, разделяют тысячи лет, не говоря уже о расстоянии и дрифте из-за относительной изолированости популяций охотников-собирателей (+ низкая плотность населения) - они и должны быть разными, имхо)

[FenriR]

Поляко также заинтересовался анализом IBD и использовал для визуализации результатов свой любый инструмент - PCA.
Цель - сравнить новые плоты с теми, что были построены привычным способом:

The Principal Component Analyses (PCA) below were produced with matrices of pairwise centiMorgan (cM) values inferred with fastIBD (see here). My aim was to create PCA that took into account haplotype information to see how they might differ from similar plots based on unlinked loci (such as here).

Обещает провести подобный анализ на выборках гораздо большего размера с включением центрально- и южно-азиатских популяций:

I'll try this again on a much larger dataset when more samples come in, and also include populations from Central and South Asia.

[Srkz]

Ожидаемо самое большое отклонение у чувашско/марийского кластера, второй по значимости финско/балтийский. Вторая волжско-уральская группа, видимо, снова татары. Мне вот интересно, откуда эта выборка. Пока что у меня ни один татарин не показал с ней резкого сходства по IBD. Группа рядом с балто-славянами, предполагаю, эрзя и мокша.

[FenriR]

В комментах к предыдущей новости Поляко запостил результаты для участников проекта.
Архив содержит три текстовых файла (PCA1, PCA2, PCA3), открываются они, например, бесплатной программой Gnuplot

Комманды, используемые для построения плотов в этой проге:
для 2D плота
plot 'PCA1.txt' using 2:3:1 with labels

чтобы использовать измерения 1&3
plot 'PCA1.txt' using 2:4:1 with labels

для 3D плота
splot 'PCA1.txt' using 2:3:4:1 with labels

(PS сначала, найдите папку с файлами PCA и откройте какой-нибудь из них (кликнете на File в левом верхнем углу меню программы, выберите Open и найдите папку с файлами PCA и нажав на All files, кликнете, например, на PCA1.txt), чтобы программа переместилась в нужную директорию, иначе может не сработать)

Т.к. при построении по дефаулту точки сливаются в одну нечитаемую массу, выбирайте интересущий Вас участок плота, зажимая правую кнопку мыши и после кликая левой, а чтобы приблизить изображение в выбранном регионе плота, используйте зажатый ctrl и колесико мыши.

получится что-то вроде этого:
"масштабированный" плот на основе PCA3.txt (я - RU67, по центру картинки)


PCA1, как я понял, отражает отношение ближневосточного и северовосточного компонентов (верхний плот в теме у Поляко)
PCA3 показывает родство с восточными финнами (предпоследний плот у Поляко)
PCA2 южная Европа - Фенноскандия (второй плот у Поляко, но восточных европейцев на нем нет)

[FenriR]

не, там был именно что другой вариант расчета, ставивший то ли какую-то французскую популяцию, то ли басков на первое место по абсолютным значениям WHG.

Это, наверное, были эксперименты Поляко с использованием бедуинов как прокси AME (древних ближневосточников)

На этом PCA видна относительная близость French_Basque к WHG.
WHG = WEF, West Eurasian Forager
NEF = North Eurasian Forager (aka. ANE)
ENF = Early Neolithic Farmer (the Near Eastern part of Oetzi)

PS Скоро на gedmatch должен появиться новый калькулятор K6 с этими компонентами, поэтому пощу сразу в тему Поляко

There will definitely be something similar to WHG, but called West Eurasian Forager, and also Ancestral South Indian (ASI), East Eurasian, Sub-Saharan, and maybe a couple more.

[FenriR]

Обещанный новый этно-калькулятор Поляко: Eurogenes ANE K=7
Как видно из названия, он, прежде всего, заточен под определение ANE, причем основан этот компонент не на дДНК сибирского MA-1, но на "не-восточноазиатской" части нескольких геномов южно-американских индейцев Karitiana (группы, которая показала наибольший, около 40%, процент ANE в научных исследованиях).

По другим компонентам:
Ancestral South Eurasian (ASE) - базальный кластер с пиком в Юго-восточной Азии. Видимо, похож на ASI в Reich et al. (также присутствует в новом кальке В.Веренича - Ancestral South Indian)
Western European/Unknown Hunter-Gatherer (WHG-UHG) - компонент охотников-собирателей Западной Евразии, но присутствовал он и у европейских земледельцев эпохи неолита: у Этци его было 40%
Early Neolithic Farmer (ENF) - видимо, компонент ранних неолитических земледельцев с земель Плодородного Полумесяца
компонент EEF (Early European Farmer) отсутствует, т.к. показал себя нестабильным (кроме того, вероятно, явлется композитным: из WHG-UHG и т.н. Basal Eurasian)
С процентами по ANE у разных популяций можно ознакомиться здесь и здесь

Итак, мои результаты:
----------------------------
 FINAL ADMIXTURE PROPORTIONS:
 ----------------------------

 18.16%  ANE
  3.41%  ASE
 66.16%  WHG-UHG
  2.20%  East_Eurasian
  0.20%  West_African
  1.45%  East_African
  8.41%  ENF

ЗЫ кальк будет доступен на gedmatch, но не известно, когда именно.

[Srkz]

 19.14%  ANE                 
  2.02%  ASE                 
 63.64%  WHG-UHG             
  6.31%  East_Eurasian       
  0.17%  West_African       
  1.61%  East_African       
  7.11%  ENF

Вечером буду дома, посмотрю, что покажут уральцы

[FenriR]

19.14%  ANE                 
  2.02%  ASE                 
 63.64%  WHG-UHG             
  6.31%  East_Eurasian       
  0.17%  West_African       
  1.61%  East_African       
  7.11%  ENF

Вечером буду дома, посмотрю, что покажут уральцы

да, было бы очень интересно посмотреть!
а пока, некоторые результаты из оригинального поста и комментариев к нему - пусть будут)

Код: [Выделить]

My results with about 6,000 missing SNPs. S Indian Brahmin
29.22% ANE
20.05% ASE
2.46% WHG-UHG
5.13% East_Eurasian
1.34% West_African
2.87% East_African
38.93% ENF

Karitiana_HGDP00998
ANE 41.56%
ASE 0.41%
WHG-UHG 0%
East_Eurasian 58.01%
West_African 0%
East_African 0.01%
ENF 0%

Lezgin_GSM536850
ANE 26.74%
ASE 3.88%
WHG-UHG 14.65%
East_Eurasian 0%
West_African 0.01%
East_African 0%
ENF 54.72%

Bedouin_HGDP00651
ANE 0%
ASE 0%
WHG-UHG 0.05%
East_Eurasian 1.49%
West_African 0%
East_African 8.19%
ENF 90.27%

Sardinian_HGDP01067
ANE 0%
ASE 0%
WHG-UHG 49.49%
East_Eurasian 1.8%
West_African 0.01%
East_African 0.01%
ENF 48.69%

[Srkz]

Вечером буду дома, посмотрю, что покажут уральцы

Мы строили, строили, и наконец, построили 
Восточноевропейские усреднения
Файл для оракула
Выборки практически те же самые, что использовались для таблицы по К18 Ancient Roots.

И мои результаты в оракуле четырех предков:

Код: [Выделить]

Using 1 population approximation:
1 Russian-North @ 1,75459
2 Russian-Upper-Volga @ 3,406909
3 Erzya @ 3,904642
4 Russian_Meshtchyora @ 4,030245
5 Russian-West @ 4,646095
6 Russian-North-West @ 6,148119
7 Belarusian-East @ 6,327378
8 Russian-South @ 6,660401
9 Moksha @ 7,196427
10 Russian-Ural @ 7,219605
11 Ukrainian-Center @ 7,448907
12 Finnish-East @ 8,638615
13 Ukrainian-East @ 8,763317
14 Ukrainian-West @ 9,70324
15 Balt @ 11,365071
16 Komi @ 14,034394
17 German-Volga @ 16,775742
18 Udmurt @ 17,046162
19 Tatar-Mishar @ 17,972079
20 Ukrainian-Carpathy @ 18,498332
29 iterations.

Using 2 populations approximation:
1 Erzya+Russian-Upper-Volga @ 1,522886
2 Russian-North-West+Russian-Ural @ 1,61601
3 Russian-North+Russian-Upper-Volga @ 1,701149
4 Russian-North+Russian-North @ 1,75459
5 Russian-Ural+Russian-West @ 1,926514
6 Russian-North+Russian-West @ 2,020704
7 Erzya+Russian-West @ 2,060368
8 Russian_Meshtchyora+Russian-North @ 2,158629
9 Erzya+Russian-North-West @ 2,272818
10 Finnish-East+Moksha @ 2,32204
11 Belarusian-East+Russian-Ural @ 2,595999
12 Erzya+Russian-North @ 2,666469
13 Russian-North+Russian-North-West @ 2,720915
14 Moksha+Russian-Upper-Volga @ 2,829072
15 Russian_Meshtchyora+Russian-Upper-Volga @ 2,830557
16 Russian-Upper-Volga+Russian-Ural @ 2,843003
17 Russian-Ural+Ukrainian-Center @ 2,869053
18 Belarusian-East+Russian-North @ 2,915193
19 Finnish-East+Russian-South @ 3,034273
20 Erzya+Russian_Meshtchyora @ 3,136766
435 iterations.

Using 3 populations approximation:
1 50% Russian-North-West +25% Finnish-East +25% Tatar-Mishar @ 1,036024
2 50% Russian-Upper-Volga +25% Balt +25% Tatar-Mishar @ 1,182437
3 50% Russian-North +25% Russian-North +25% Russian-West @ 1,232327
4 50% Erzya +25% Finnish-East +25% Ukrainian-Center @ 1,263711
5 50% Erzya +25% Finnish-East +25% Ukrainian-East @ 1,269472
6 50% Erzya +25% Belarusian-East +25% Finnish-East @ 1,309834
7 50% Erzya +25% Finnish-East +25% Russian-South @ 1,320103
8 50% Russian-West +25% Russian-North +25% Russian-Ural @ 1,32433
9 50% Russian-North +25% Russian-North +25% Russian-Upper-Volga @ 1,36895
10 50% Russian-North +25% Erzya +25% Russian-North-West @ 1,384719
11 50% Russian-North +25% Russian-North +25% Russian-North-West @ 1,407865
12 50% Russian-North-West +25% Russian-North-West +25% Udmurt @ 1,417771
13 50% Russian-North +25% Erzya +25% Russian-West @ 1,433136
14 50% Erzya +25% Finnish-East +25% Ukrainian-West @ 1,442352
15 50% Russian-North-West +25% Russian-West +25% Udmurt @ 1,443111
16 50% Russian-Upper-Volga +25% Erzya +25% Russian-North @ 1,446879
17 50% Russian-North +25% Finnish-East +25% Ukrainian-West @ 1,450149
18 50% Russian-South +25% Finnish-East +25% Russian-Ural @ 1,465126
19 50% Russian-North-West +25% Russian-Upper-Volga +25% Udmurt @ 1,478957
20 50% Russian_Meshtchyora +25% Erzya +25% Finnish-East @ 1,485304
10095 iterations.

Using 4 populations approximation:
1 Balt+Belarusian-East+Finnish-East+Tatar-Mishar @ 1,020687
2 Balt+Finnish-East+Tatar-Mishar+Ukrainian-Center @ 1,029996
3 Finnish-East+Russian-North-West+Russian-North-West+Tatar-Mishar @ 1,036024
4 Balt+Finnish-East+Russian-South+Tatar-Mishar @ 1,147077
5 Balt+Finnish-East+Tatar-Mishar+Ukrainian-East @ 1,164424
6 Balt+Russian-Upper-Volga+Russian-Upper-Volga+Tatar-Mishar @ 1,182437
7 Erzya+Finnish-East+Russian-North+Ukrainian-East @ 1,223145
8 Russian-North+Russian-North+Russian-North+Russian-West @ 1,232327
9 Erzya+Finnish-East+Russian-North+Russian-South @ 1,251304
10 Erzya+Finnish-East+Russian-North+Ukrainian-West @ 1,256411
11 Finnish-East+Russian_Meshtchyora+Russian-Ural+Ukrainian-East @ 1,260282
12 Erzya+Erzya+Finnish-East+Ukrainian-Center @ 1,263711
13 Erzya+Erzya+Finnish-East+Ukrainian-East @ 1,269472
14 Balt+Finnish-East+Russian-West+Tatar-Mishar @ 1,270177
15 Finnish-East+Komi+Russian-North-West+Ukrainian-East @ 1,275902
16 Balt+Belarusian-East+Finnish-East+Tatar-Kazan @ 1,279639
17 Finnish-East+Russian-North-West+Russian-West+Tatar-Mishar @ 1,288135
18 Finnish-East+Russian-Upper-Volga+Russian-Ural+Ukrainian-West @ 1,302516
19 Finnish-East+Russian-North+Russian-Ural+Ukrainian-West @ 1,30255
20 Balt+Finnish-East+Russian_Meshtchyora+Tatar-Mishar @ 1,308335
21 Belarusian-East+Erzya+Erzya+Finnish-East @ 1,309834
22 Erzya+Erzya+Finnish-East+Russian-South @ 1,320103
23 Russian-North+Russian-Ural+Russian-West+Russian-West @ 1,32433
24 Balt+Finnish-East+Russian-West+Tatar-Kazan @ 1,326159
25 Balt+Finnish-East+Tatar-Kazan+Ukrainian-Center @ 1,329465
26 Finnish-East+Russian-North+Russian-Ural+Ukrainian-East @ 1,33938
27 Finnish-East+Russian_Meshtchyora+Russian-Ural+Ukrainian-Center @ 1,342738
28 Finnish-East+Komi+Russian-North-West+Ukrainian-West @ 1,349819
29 Finnish-East+Russian_Meshtchyora+Russian-South+Russian-Ural @ 1,365788
30 Finnish-East+Russian_Meshtchyora+Russian-Ural+Ukrainian-West @ 1,36778
31 Russian-North+Russian-North+Russian-North+Russian-Upper-Volga @ 1,36895
32 Balt+Finnish-East+Russian-North-West+Tatar-Kazan @ 1,372125
33 Finnish-East+Russian-North-West+Udmurt+Ukrainian-East @ 1,377249
34 Balt+Finnish-East+Udmurt+Ukrainian-West @ 1,37862
35 Finnish-East+Moksha+Russian-North+Russian-West @ 1,37999
36 Erzya+Russian-North+Russian-North+Russian-North-West @ 1,384719
37 Erzya+Finnish-East+Russian-North+Ukrainian-Center @ 1,384848
38 Finnish-East+Russian-Ural+Russian-West+Ukrainian-West @ 1,3884
39 Erzya+Finnish-East+Moksha+Russian-West @ 1,393313
40 Finnish-East+Komi+Russian-West+Ukrainian-East @ 1,398212

[FenriR]

мои:

Код: [Выделить]

Least-squares method.

Using 1 population approximation:
1 Russian-West @ 1,695701
2 Russian-North-West @ 2,45539
3 Belarusian-East @ 3,129181
4 Russian-Upper-Volga @ 4,144445
5 Russian_Meshtchyora @ 4,286486
6 Ukrainian-Center @ 4,442743
7 Russian-South @ 4,730027
8 Ukrainian-East @ 5,930132
9 Russian-North @ 6,565909
10 Ukrainian-West @ 7,230266
11 Erzya @ 8,274529
12 Balt @ 8,382436
13 Moksha @ 10,008962
14 Finnish-East @ 10,770304
15 Russian-Ural @ 12,285796
16 German-Volga @ 15,464125
17 Ukrainian-Carpathy @ 17,970434
18 Komi @ 18,870312
19 Tatar-Mishar @ 21,877301
20 Udmurt @ 21,910776
29 iterations.

Using 2 populations approximation:
1 Russian-West+Russian-West @ 1,695701
2 Belarusian-East+Russian-North-West @ 1,886507
3 Russian-North-West+Russian-West @ 1,8936
4 Belarusian-East+Russian-West @ 1,986263
5 Russian-North-West+Russian-South @ 2,148453
6 Russian_Meshtchyora+Russian-North-West @ 2,174454
7 Belarusian-East+Russian-Upper-Volga @ 2,179277
8 Russian-Upper-Volga+Ukrainian-Center @ 2,210892
9 Russian-Upper-Volga+Ukrainian-East @ 2,340021
10 Russian-North-West+Ukrainian-Center @ 2,352584
11 Russian-North-West+Russian-North-West @ 2,45539
12 Russian-West+Ukrainian-Center @ 2,466168
13 Russian-South+Russian-Upper-Volga @ 2,581287
14 Russian-South+Russian-West @ 2,599611
15 Balt+Russian-South @ 2,671086
16 Russian_Meshtchyora+Russian-West @ 2,690294
17 Russian-North-West+Ukrainian-East @ 2,738742
18 Balt+Ukrainian-West @ 2,747334
19 Russian-Upper-Volga+Russian-West @ 2,777645
20 Russian-Upper-Volga+Ukrainian-West @ 2,832028
435 iterations.

Using 3 populations approximation:
1 50% Russian-North-West +25% Russian-South +25% Russian-West @ 1,623025
2 50% Russian-North-West +25% Russian-Upper-Volga +25% Ukrainian-East @ 1,635728
3 50% Russian-North-West +25% Russian-Upper-Volga +25% Ukrainian-West @ 1,636074
4 50% Russian-West +25% Belarusian-East +25% Russian-North-West @ 1,636343
5 50% Balt +25% Russian-North +25% Ukrainian-Carpathy @ 1,6416
6 50% Russian-South +25% Balt +25% Russian-West @ 1,65324
7 50% Russian-West +25% Russian-North-West +25% Russian-South @ 1,665998
8 50% Russian-South +25% Balt +25% Russian-Upper-Volga @ 1,674439
9 50% Balt +25% Russian-Upper-Volga +25% Ukrainian-Carpathy @ 1,67571
10 50% Russian-West +25% Belarusian-East +25% Russian-West @ 1,67727
11 50% Balt +25% German-Volga +25% Russian-North @ 1,691218
12 50% Russian-West +25% Balt +25% Ukrainian-West @ 1,699658
13 50% Russian-North-West +25% Russian-North-West +25% Russian-South @ 1,710583
14 50% Russian-North-West +25% Belarusian-East +25% Russian-West @ 1,724885
15 50% Ukrainian-East +25% Balt +25% Russian-Upper-Volga @ 1,725784
16 50% Russian-West +25% Russian-North-West +25% Ukrainian-Center @ 1,731084
17 50% Russian-West +25% Russian-North-West +25% Russian-West @ 1,736073
18 50% Ukrainian-East +25% Balt +25% Russian-North @ 1,739609
19 50% Russian-West +25% Russian-North-West +25% Ukrainian-East @ 1,739707
20 50% Russian-North-West +25% Russian-West +25% Ukrainian-East @ 1,744123
8182 iterations.

Using 4 populations approximation:
1 Balt+Russian-South+Russian-Upper-Volga+Ukrainian-East @ 1,578453
2 Balt+Russian-South+Russian-Upper-Volga+Ukrainian-West @ 1,595899
3 Balt+Russian-North+Russian-West+Ukrainian-West @ 1,616907
4 Russian-North-West+Russian-North-West+Russian-South+Russian-West @ 1,623025
5 Balt+Russian_Meshtchyora+Russian-West+Ukrainian-East @ 1,630984
6 Balt+Belarusian-East+Russian-North+Ukrainian-East @ 1,632774
7 Russian-North-West+Russian-North-West+Russian-Upper-Volga+Ukrainian-East @ 1,635728
8 Russian-North-West+Russian-North-West+Russian-Upper-Volga+Ukrainian-West @ 1,636074
9 Balt+Russian_Meshtchyora+Russian-West+Ukrainian-West @ 1,636342
10 Belarusian-East+Russian-North-West+Russian-West+Russian-West @ 1,636343
11 Balt+Balt+Russian-North+Ukrainian-Carpathy @ 1,6416
12 Russian-North-West+Russian-Upper-Volga+Russian-West+Ukrainian-East @ 1,648343
13 Balt+Russian_Meshtchyora+Russian-Upper-Volga+Ukrainian-West @ 1,651214
14 Balt+Russian-South+Russian-South+Russian-West @ 1,65324
15 Balt+Russian-North+Russian-North-West+Ukrainian-West @ 1,661125
16 Balt+Belarusian-East+Russian-Upper-Volga+Ukrainian-West @ 1,66599
17 Russian-North-West+Russian-South+Russian-West+Russian-West @ 1,665998
18 Balt+Belarusian-East+Russian-North+Ukrainian-West @ 1,67392
19 Balt+Russian-South+Russian-South+Russian-Upper-Volga @ 1,674439
20 Balt+Balt+Russian-Upper-Volga+Ukrainian-Carpathy @ 1,67571
21 Belarusian-East+Russian-West+Russian-West+Russian-West @ 1,67727
22 Balt+Balt+German-Volga+Russian-North @ 1,691218
23 Russian-West+Russian-West+Russian-West+Russian-West @ 1,695701
24 Balt+Russian-West+Russian-West+Ukrainian-West @ 1,699658
25 Balt+Russian-North+Ukrainian-Center+Ukrainian-East @ 1,706828
26 Russian-North-West+Russian-North-West+Russian-North-West+Russian-South @ 1,710583
27 Russian-North-West+Russian-Upper-Volga+Russian-West+Ukrainian-West @ 1,715424
28 Belarusian-East+Russian-North-West+Russian-North-West+Russian-West @ 1,724885
29 Balt+Russian-North+Russian-West+Ukrainian-East @ 1,72531
30 Balt+Russian-Upper-Volga+Ukrainian-East+Ukrainian-East @ 1,725784
31 Balt+Russian-Upper-Volga+Russian-West+Ukrainian-West @ 1,729611
32 Russian-North-West+Russian-West+Russian-West+Ukrainian-Center @ 1,731084
33 Balt+Russian_Meshtchyora+Russian-North-West+Ukrainian-West @ 1,731365
34 Russian-North-West+Russian-West+Russian-West+Russian-West @ 1,736073
35 Balt+Erzya+Russian-North-West+Ukrainian-West @ 1,739135
36 Balt+Russian-North+Ukrainian-East+Ukrainian-East @ 1,739609
37 Russian-North-West+Russian-West+Russian-West+Ukrainian-East @ 1,739707
38 Balt+Russian_Meshtchyora+Russian-South+Russian-West @ 1,743493
39 Russian-North-West+Russian-North-West+Russian-West+Ukrainian-East @ 1,744123
40 Balt+Russian_Meshtchyora+Russian-Upper-Volga+Ukrainian-East @ 1,7462
15141 iterations.


Gaussian method.
Noise dispersion set to 0,77434

Using 1 population approximation:
1 Russian-North-West @ 2,66312
2 Russian-West @ 2,981733
3 Belarusian-East @ 3,926462
4 Ukrainian-Center @ 4,404857
5 Russian-Upper-Volga @ 4,742105
6 Russian_Meshtchyora @ 4,904558
7 Ukrainian-East @ 5,063647
8 Ukrainian-West @ 5,52092
9 Russian-South @ 5,542526
10 Russian-North @ 6,517434
11 Erzya @ 6,949305
12 Moksha @ 7,906772
13 Balt @ 8,125718
14 Russian-Ural @ 8,790997
15 German-Volga @ 9,205375
16 Ukrainian-Carpathy @ 10,237389
17 Komi @ 10,966824
18 Tatar-Mishar @ 12,015173
19 Udmurt @ 12,121858
20 Tatar-Kazan @ 13,181675
29 iterations.

Using 2 populations approximation:
1 Russian-North-West+Russian-North-West @ 2,66312
2 Russian-North-West+Russian-West @ 2,719217
3 Russian-West+Russian-West @ 2,981733
4 Belarusian-East+Russian-North-West @ 3,051696
5 Belarusian-East+Russian-West @ 3,164163
6 Russian-North-West+Ukrainian-Center @ 3,165631
7 Russian-West+Ukrainian-Center @ 3,266839
8 Russian-North-West+Ukrainian-East @ 3,35268
9 Russian-West+Ukrainian-East @ 3,476871
10 Russian-North-West+Ukrainian-West @ 3,514938
11 Russian-Upper-Volga+Ukrainian-East @ 3,521772
12 Russian-Upper-Volga+Ukrainian-Center @ 3,538141
13 Belarusian-East+Russian-Upper-Volga @ 3,548063
14 Russian-Upper-Volga+Ukrainian-West @ 3,569421
15 Russian-North-West+Russian-Upper-Volga @ 3,599735
16 Russian-West+Ukrainian-West @ 3,613665
17 Russian-North-West+Russian-South @ 3,666453
18 Russian_Meshtchyora+Russian-North-West @ 3,679198
19 Balt+Ukrainian-Center @ 3,683438
20 Balt+Russian-West @ 3,726753
435 iterations.

Using 3 populations approximation:
1 50% Russian-West +25% Balt +25% Ukrainian-West @ 2,537977
2 50% Balt +25% Russian-Upper-Volga +25% Ukrainian-Carpathy @ 2,591136
3 50% Russian-West +25% Balt +25% Ukrainian-East @ 2,593065
4 50% Russian-West +25% Balt +25% Ukrainian-Center @ 2,608504
5 50% Russian-North-West +25% Russian-North-West +25% Russian-West @ 2,658095
6 50% Russian-North-West +25% Russian-West +25% Russian-West @ 2,719217
7 50% Russian-North-West +25% Russian-North-West +25% Ukrainian-Center @ 2,733927
8 50% Russian-North-West +25% Russian-North-West +25% Ukrainian-East @ 2,73508
9 50% Russian-North-West +25% Russian-North-West +25% Ukrainian-West @ 2,73892
10 50% Balt +25% Russian-West +25% Ukrainian-Carpathy @ 2,752987
11 50% Russian-North-West +25% Russian-West +25% Ukrainian-Center @ 2,754191
12 50% Russian-North-West +25% Belarusian-East +25% Russian-North-West @ 2,756521
13 50% Russian-West +25% Balt +25% Belarusian-East @ 2,765722
14 50% Russian-North-West +25% Russian-West +25% Ukrainian-West @ 2,773053
15 50% Russian-North-West +25% Russian-West +25% Ukrainian-East @ 2,773223
16 50% Russian-North-West +25% Belarusian-East +25% Russian-West @ 2,775069
17 50% Russian-North-West +25% Balt +25% Ukrainian-West @ 2,813952
18 50% Russian-West +25% Russian-North-West +25% Russian-West @ 2,831873
19 50% Russian-West +25% Russian-North-West +25% Ukrainian-Center @ 2,841889
20 50% Russian-North-West +25% Balt +25% Ukrainian-East @ 2,853457
12180 iterations.

Using 4 populations approximation:
1 Balt+Russian-West+Russian-West+Ukrainian-West @ 2,537977
2 Balt+Balt+Russian-Upper-Volga+Ukrainian-Carpathy @ 2,591136
3 Balt+Russian-West+Russian-West+Ukrainian-East @ 2,593065
4 Balt+Russian-West+Russian-West+Ukrainian-Center @ 2,608504
5 Balt+Russian-North-West+Russian-West+Ukrainian-West @ 2,622624
6 Balt+Russian-Upper-Volga+Russian-West+Ukrainian-West @ 2,649951
7 Balt+Russian-North-West+Russian-Upper-Volga+Ukrainian-West @ 2,652137
8 Russian-North-West+Russian-North-West+Russian-North-West+Russian-West @ 2,658095
9 Russian-North-West+Russian-North-West+Russian-North-West+Russian-North-West @ 2,66312
10 Balt+Russian-North-West+Russian-West+Ukrainian-East @ 2,672938
11 Balt+Russian-North-West+Russian-West+Ukrainian-Center @ 2,699301
12 Russian-North-West+Russian-North-West+Russian-West+Russian-West @ 2,719217
13 Russian-North-West+Russian-North-West+Russian-North-West+Ukrainian-Center @ 2,733927
14 Russian-North-West+Russian-North-West+Russian-North-West+Ukrainian-East @ 2,73508
15 Russian-North-West+Russian-North-West+Russian-North-West+Ukrainian-West @ 2,73892
16 Balt+Balt+Russian-West+Ukrainian-Carpathy @ 2,752987
17 Balt+Russian-Upper-Volga+Russian-West+Ukrainian-East @ 2,753471
18 Russian-North-West+Russian-North-West+Russian-West+Ukrainian-Center @ 2,754191
19 Balt+Russian-North-West+Russian-Upper-Volga+Ukrainian-East @ 2,755956
20 Belarusian-East+Russian-North-West+Russian-North-West+Russian-North-West @ 2,756521
21 Balt+Belarusian-East+Russian-West+Russian-West @ 2,765722
22 Russian-North-West+Russian-North-West+Russian-West+Ukrainian-West @ 2,773053
23 Russian-North-West+Russian-North-West+Russian-West+Ukrainian-East @ 2,773223
24 Belarusian-East+Russian-North-West+Russian-North-West+Russian-West @ 2,775069
25 Balt+Russian-North-West+Russian-North-West+Ukrainian-West @ 2,813952
26 Balt+Russian-Upper-Volga+Ukrainian-Center+Ukrainian-East @ 2,822577
27 Russian-North-West+Russian-West+Russian-West+Russian-West @ 2,831873
28 Balt+Russian-Upper-Volga+Ukrainian-Center+Ukrainian-West @ 2,832337
29 Russian-North-West+Russian-West+Russian-West+Ukrainian-Center @ 2,841889
30 Balt+Russian-North-West+Russian-North-West+Ukrainian-East @ 2,853457
31 Balt+Belarusian-East+Russian-North-West+Russian-West @ 2,853829
32 Balt+Russian-Upper-Volga+Ukrainian-East+Ukrainian-East @ 2,856129
33 Russian-North-West+Russian-North-West+Russian-Upper-Volga+Ukrainian-West @ 2,857253
34 Balt+Russian-West+Russian-West+Russian-West @ 2,857726
35 Balt+Balt+Russian-North-West+Ukrainian-Carpathy @ 2,859136
36 Belarusian-East+Russian-North-West+Russian-West+Russian-West @ 2,859628
37 Balt+Belarusian-East+Russian-Upper-Volga+Ukrainian-West @ 2,865944
38 Balt+Belarusian-East+Russian-Upper-Volga+Ukrainian-East @ 2,871636
39 Russian-North-West+Russian-West+Russian-West+Ukrainian-West @ 2,876541
40 Russian-North-West+Russian-West+Russian-West+Ukrainian-East @ 2,877614
35960 iterations.

[Srkz]

Очень маленькие расстояния из-за небольшого количества компонентов

[FenriR]

да, а так, мои результаты, вроде, более-менее, в согласии с остальными калькуляторами Поляко)