G25 от Давидски (Eurogenes)

[Roaring]

В прошлом году Давид Весоловский, автор калькуляторов Eurogenes выпустил новый калькулятор под названием G25. Поскольку получил вопросы по поводу данного калькулятора решил создать тему на форуме.

Согласно автору калькулятор представляет ценность из-за его заточенности на сравнение с древними образцами.

1.Как пользоваться?

Для начала нужно получить результаты или координаты как их называет автор путём отправки запроса на почту eurogenesblog@gmail.com и оплаты 12$ за услугу через Paypal.

Далее автор отсылает вам координаты и из можно прокручивать на  сайте, специально созданном для этого сайте.

Адрес: https://vahaduo.github.io/vahaduo/

В графу Sourse вводим популяции с которыми хотим сравнить, в Target, то, кого хотим сравнивать.

2. В чём интерес?

За последний год G25 стал основным этно-популяционным тестом, практически все новые образцы из научных работ  быстро переводятся в формат G25, плюс энтузиасты создают свои подборки, некотрые из которых весьма интересны.

3. Примеры результатов:

Мои результаты в сравнении с базовыми компонентами:

Distance: 5.9081% / 0.05908075
57.4   Yamnaya_Samara
25.4   Barcin_N
15.2   WHG
1.6   Han
0.4   Nganassan

Мои результаты в сравнении с современными популяциями:
Distance: 0.9603% / 0.00960344 | ADC: 0.25x
42.6   Russian_Tver
22.4   Estonian
13.6   Cossack_Kuban
13.2   Ingrian
4.6   Kaitag
2.4   Icelandic
1.2   Tajik_Rushan



Сайт с подборками калькуляторов: http://g25vahaduo.genetics.ovh/

[R1a-Stolin]

Мои результаты в сравнении с современными популяциями:

Как называется этот калькулятор, у Вас есть его координаты? Scaled или unscaled?

[Roaring]

Мои результаты в сравнении с современными популяциями:

Как называется этот калькулятор, у Вас есть его координаты? Scaled или unscaled?

Вот отсюда, модерн скейлед.

https://eurogenes.blogspot.com/2019/07/getting-most-out-of-global25_12.html

[R1a-Stolin]

Я в сравнении с современными популяциями:

Distance: 0.8937% / 0.00893748 | ADC: 0.25x
55.6   Ukrainian
17.8   Moldovan_o
9.6   Croatian
7.6   Polish
6.4   Belarusian
2.8   Hungarian
0.2   Assyrian

[Roaring]

Я в сравнении с современными популяциями:

Distance: 0.8937% / 0.00893748 | ADC: 0.25x
55.6   Ukrainian
17.8   Moldovan_o
9.6   Croatian
7.6   Polish
6.4   Belarusian
2.8   Hungarian
0.2   Assyrian

Довольно южные результаты, а что у вас по древним компонентам?

Armenia_EBA,0.107753,0.128634,-0.065242,-0.045113,-0.048932,-0.00344,0.009479,-0.005154,-0.056244,-0.016948,0.003139,0.009142,-0.014222,0.003165,0.005338,-0.000442,0.012256,-0.000971,-0.002598,0.000292,0.007528,-0.004122,0.004642,-0.00237,-0.001597
Barcin_N,0.117977651830018,0.181018118861759,0.00271526882647004,-0.101018734131967,0.051948182859461,-0.0472580222655371,-0.00442995052737612,-0.0075689153780446,0.0367836121278892,0.0809766157370447,0.00854163106203961,0.0121616751868318,-0.0229383440771125,0.000770686966283977,-0.0411978972527725,-0.00909564603532921,0.0231562069432798,0.000741128278370216,0.0121550015220073,-0.00919816194138807,-0.0131143576167497,0.00612699324505911,-0.00388230311799581,-0.00332577136917137,-0.00513726380478947
Clovis:Anzick,0.048944,-0.294504,0.114645,0.0969,-0.097864,-0.012271,-0.259922,-0.314756,-0.011862,-0.024055,0.006496,-0.002398,-0.000743,0.010597,-0.012079,0.006232,0.008345,0.00038,-0.003268,0.005753,-0.001747,0.003586,-0.006532,-0.000723,0.003712
Dinka,-0.577462,0.051115,0.000754,-0.007591,-0.005899,-0.001255,-0.016647,0.019691,0.080787,-0.097466,-0.019865,0.022055,-0.039569,-0.001216,0.009478,-0.021391,0.017059,-0.011212,0.022081,-0.022386,0.001996,0.003978,0.000924,0.001366,0.009799
Ethiopia_4500BP,-0.511066,0.043668,0.000754,0.000969,-0.00277,-0.011435,0.050997,-0.045229,0.089172,-0.087838,-0.012991,-0.002997,-0.031219,0.000688,0.02158,-0.029965,0.027772,0.039273,0.00176,-0.009004,0.000374,0.006183,-0.003451,-0.00241,-0.000838
Ganj_Dareh_N,0.044012,0.06804,-0.15374,0.002369,-0.121869,0.019057,0.017391,-0.003307,-0.083037,-0.0554,-0.000325,-0.004796,0.006145,-0.009496,0.029587,0.058826,-0.008084,0.009882,0.011103,-0.036226,0.0094,-0.02708,-0.011626,-0.037917,0.025746
Han,0.0209434519408812,-0.450691955965491,-0.00871148748492472,-0.0652140125379508,0.0789686239439437,0.038263798494138,0.00256161595482227,-0.00553823076442288,-0.0150734068047008,-0.00328024999047329,-0.0470601650528342,-0.00666906402728299,0.00726950761743875,-0.00761053379205427,-0.0042209013492381,0.00070272483946421,0.00132991729066134,-0.00111485963242015,-0.00177234251768669,-0.0103674728068127,0.011829125614347,0.00704820615476023,0.0146541536739588,-0.000771193360967274,-0.00246684462421126
Jarawa,-0.021867,-0.243353,-0.132588,0.098702,0.032557,-0.004829,-0.009982,0.006571,0.054791,0.024084,0.023033,0.002769,-0.003826,0.010046,-0.010736,-0.011431,0.009937,-0.00204,-0.006106,0.028461,-0.004315,0.011344,-0.012805,0.001934,0.004651
Levant_N,0.00615,0.0168,-0.0071,-0.04625,0.01025,-0.02515,-0.00645,-0.00645,0.03675,0.02375,0.0052,-0.0088,0.02085,-0.0031,-0.01465,0.00595,0.00775,-0.00645,-0.00725,0.01445,-0.0042,0.0059,0.00125,-9e-04,-0.0037
Morocco_Iberomaurusian,-0.189857,0.081445,-0.024287,-0.085595,0.027636,-0.05522,-0.070597,0.018415,0.155397,0.003499,0.020916,-0.031832,0.074717,-0.051333,0.071199,-0.036303,0.005268,-0.066106,-0.142416,0.038994,-0.037684,-0.125532,0.073012,-0.013761,0.016454
Nganassan,0.049399,-0.406009,0.154242,0.001809,-0.158922,-0.085731,0.027966,0.043014,0.03031,0.012429,0.103409,0.009532,-0.003152,-0.027112,-0.022095,-0.013842,-0.000991,0.013733,0.02426,-0.001476,0.043548,-0.012736,0.034559,0.002362,0.013268
Shahr_I_Sokhta_BA3,0.033009,-0.081242,-0.180641,0.120157,-0.097557,0.065539,0.0047,0.009461,0.035996,0.026789,-0.002273,0.003747,-0.005649,0.007982,0.003529,0.003182,0.008736,0.001647,0.000126,-0.002001,0.001373,-0.008161,0.000246,-0.001928,-0.008023
Tepecik_Ciftlik_N,0.0097,0.01705,-0.00375,-0.0302,0.00815,-0.01225,7e-04,-0.003,0.01125,0.0318,0.0094,0.0076,-0.00785,0.00045,-0.0276,0.00355,0.01325,-0.00045,0.009,4e-04,-8e-04,0.00415,-0.0067,-0.00395,-0.00655
WHG,0.124636303669918,0.116278118427329,0.1847891284681,0.189278907118569,0.154644323974403,0.0464352948197812,0.013160595731197,0.0372676778522623,0.0890701311186865,0.0177680207817303,-0.0153457059954894,-0.0158109270759181,0.0159066935596308,-0.00302769879611562,0.0533380781431052,0.0582068310424129,0.00501978585200604,0.0163428287025227,-0.00930165576658264,0.0555891636022705,0.094458313186294,0.0111905729299263,-0.0496072065077243,-0.160866115139267,0.0170044629435922
Yamnaya_Samara,0.125368186256765,0.087625971411533,0.043638141248077,0.116234368052845,-0.0298077319148034,0.0465348587852507,0.00376017020891342,-0.00174708104656023,-0.0563025490588719,-0.0735973289112539,0.000858385205208011,-0.000342595064412785,-0.00118928549978548,-0.0259713250277347,0.0358883833722727,0.0160054200511477,-0.000316702852844745,-0.000705782160478713,-0.00393258922045006,0.0144355490786198,-0.00229956704585233,-0.000830204493387021,0.0106521770217543,0.0178510778240273,-0.00316486585307182
Yoruba,-0.630062125250819,0.0625007580664627,0.0221128476262357,0.0167079010725635,0.000503478833874871,0.0124739425309571,-0.0444170105927898,0.0477672403431473,-0.0488811971007258,0.032769332932607,0.00462076258308626,0.000790246620581196,0.0230559346809037,0.000950835044652857,0.012523319298979,-0.00960677891384516,0.00707633344275127,0.000449111067832891,0.00602206792055686,-0.00299005919587556,0.00155413248445877,0.00231564485368763,-0.00175911467946521,-0.000471030445003293,-0.000424512824894608

[andronn]

результаты мамы:

Target: PMorozova_scaled
Distance: 6.1764% / 0.06176448
52.6 Yamnaya_RUS_Samara
32.0 Anatolia_Barcin_N
15.0 WHG
0.2 Han
0.2 Nganassan

[i.vet]

У меня вот так.

Современные:
Target: Ivan_scaled
Distance: 2.1716% / 0.02171643 | ADC: 0.25x
69.2   Belarusian
19.2   Russian_Smolensk
7.6   Lithuanian_PZ
2.4   Chuvash
0.8   Dolgan
0.6   Russian_Pinega
0.2   Yoruba

И древние:
Target: Ivan_scaled
Distance: 8.2540% / 0.08254042
54.0 Yamnaya_RUS_Samara
28.4 Anatolia_Barcin_N
16.6 WHG
1.0 Nganassan

[R1a-Stolin]

Довольно южные результаты, а что у вас по древним компонентам?

Мало WHG, за счёт повышенного Barcin_N.

Distance: 6.0156% / 0.06015621
52.0   Yamnaya_Samara
35.2   Barcin_N
12.8   WHG

[andronn]

Разобрался, тогда у матери вот такие результаты:

Target: PMorozova_scaled
Distance: 0.9217% / 0.00921681 | ADC: 0.25x RC
28.2   Polish
17.8   Mordovian
16.8   Russian_Kursk
14.8   Ukrainian
10.6   German
4.0   Lithuanian_VZ
3.4   Belarusian
3.2   Russian_Orel
1.2   Dutch

[Гордий]

Решил очень грубо прикинуть "охотничьи" компоненты в китах бронзового века. Взял Лошбур как пример WHG, Самарскую культуру как пример EHG, и Котиас как пример CHG. Для примера "срубники".
На eurogenes K13 компонент EHG отсутствует:

Target: mur003_Russia_Srubnaya_Alakul.SG_3734_ybp
Distance: 6.6203% / 6.62029564
79.0   Loschbour_Loschbour_Luxembourg_6000_BC
21.0   KK1_Georgia_Kotias.SG_9720_ybp

На MDLP K16 Ancient также (правда не тот срубник, но они все похожи):

Target: Srubnaya
Distance: 13.8571% / 13.85714509
57.0   Luxembourg_Mesolithic
43.0   Kotias

А вот на G25 EHG преобладает над остальными:

Target: RUS_Srubnaya_Alakul_MLBA:mur003
Distance: 10.4590% / 0.10458963
45.0   RUS_Samara_HG
39.0   GEO_CHG
16.0   LUX_Loschbour

Как такое объяснить? Неужели на G25 часть данных неверная?

[Гордий]

По хвалынцам во всех трех калькуляторах совпадает - EHG плюс некоторая кавказская примесь.

[Roaring]

Разобрался, тогда у матери вот такие результаты:

Target: PMorozova_scaled
Distance: 0.9217% / 0.00921681 | ADC: 0.25x RC
28.2   Polish
17.8   Mordovian
16.8   Russian_Kursk
14.8   Ukrainian
10.6   German
4.0   Lithuanian_VZ
3.4   Belarusian
3.2   Russian_Orel
1.2   Dutch

У матери были немцы в роду?

[andronn]

Разобрался, тогда у матери вот такие результаты:

Target: PMorozova_scaled
Distance: 0.9217% / 0.00921681 | ADC: 0.25x RC
28.2   Polish
17.8   Mordovian
16.8   Russian_Kursk
14.8   Ukrainian
10.6   German
4.0   Lithuanian_VZ
3.4   Belarusian
3.2   Russian_Orel
1.2   Dutch

У матери были немцы в роду?

Точно сказать не могу,т.к. материнскую родословную практически не знаю. Южная Бессарабия, кого там только не было, нем. колоний рядом было много. В кузенах самые близкие поляки, немцем тоже прилично, есть кондовые с самой Германии, но в основном из наших бывших немцев( Казахстан, Киргизия,Украина). А так все считали себя русскими (дедушка, бабушка), говорили только на русском, да и фамилии русские. Вообще материнские результаты, калькуляторов и ее кузены меня всегда поражали( в отличии от папы).
Я использовал вот эту табл. Global25 datasheet modern scaled,  я спросил как сравнивать с совр. популяциями, он мне сбросил на нее ссылку .

[andronn]

Target: PMorozova_scaled
Distance: 1.5858% / 0.01585786 | ADC: 0.25x RC
39.0   Cossack_Ukrainian
21.4   Russian_Orel
18.6   Slovakian
8.4   Dutch
6.4   Estonian
4.8   Cossack_Kuban
1.4   Uttar_Pradesh
Вот для при мера я скопировал табл. Global25 pop averages modern scaled получились такие данные. Может что не так делаю? И вообще он(Веселовски),скинул  мне координаты разные: PMorozova_scaled,0.133173,0.118817,0.065996,0.06137,0.033545,0.02259,0.012691,0.01823,0.002045,-0.015126,-0.000325,-0.00045,0.014271,0.019405,-0.009772,0.006762,0.001043,-0.005068,0.001257,0.004002,-0.008485,-0.001607,-0.000616,0.001687,-0.001557

PMorozova,0.0117,0.0117,0.0175,0.019,0.0109,0.0081,0.0054,0.0079,0.001,-0.0083,-0.0002,-0.0003,0.0096,0.0141,-0.0072,0.0051,0.0008,-0.004,0.001,0.0032,-0.0068,-0.0013,-0.0005,0.0014,-0.0013
я использую первые PMorozova_scaled, потому что вторые дают какие то неадекватные данные.Для чего они вообще? Объясните!

[Roaring]

Точно сказать не могу,т.к. материнскую родословную практически не знаю. Южная Бессарабия, кого там только не было, нем. колоний рядом было много. В кузенах самые близкие поляки, немцем тоже прилично, есть кондовые с самой Германии, но в основном из наших бывших немцев( Казахстан, Киргизия,Украина). А так все считали себя русскими (дедушка, бабушка), говорили только на русском, да и фамилии русские. Вообще материнские результаты, калькуляторов и ее кузены меня всегда поражали( в отличии от папы).
Я использовал вот эту табл. Global25 datasheet modern scaled,  я спросил как сравнивать с совр. популяциями, он мне сбросил на нее ссылку .

Ну похоже на то, у меня документально 1/8 немцев выдаёт 11.8 Norwegian.