https://link.springer.com/article/10.1007%2Fs00438-018-1461-2
Reconstruction of Y-chromosome phylogeny reveals two neolithic expansions of Tibeto-Burman populations Ling-Xiang Wang
19
Yan Lu
2
Chao Zhang
23
Lan-Hai Wei
159
Shi Yan
1
Yun-Zhi Huang
19
Chuan-Chao Wang
6
Swapan Mallick
7
Shao-Qing Wen
19
Li Jin
19
Shu-Hua Xu
23489Email author
Hui Li
19Email author
1.MOE Key Laboratory of Contemporary AnthropologyFudan UniversityShanghaiChina
2.Chinese Academy of Sciences (CAS) Key Laboratory of Computational Biology, Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology (PICB), Shanghai Institutes for Biological SciencesChinese Academy of SciencesShanghaiChina
3.University of Chinese Academy of SciencesBeijingChina
4.School of Life Science and TechnologyShanghaiTech UniversityShanghaiChina
5.Institut National des Langues et Civilisations OrientalesParisFrance
6.Department of Anthropology and EthnologyXiamen UniversityXiamenChina
7.Department of GeneticsHarvard Medical SchoolBostonUSA
8.Center for Excellence in Animal Evolution and GeneticsChinese Academy of SciencesKunmingChina
9.Collaborative Innovation Center of Genetics and DevelopmentShanghaiChina
Original Article
First Online: 19 June 2018
Abstract
Diffusion of Tibeto-Burman populations across the Tibetan Plateau led to the largest human community in a high-altitude environment and has long been a focus of research on high-altitude adaptation, archeology, genetics, and linguistics. However, much uncertainty remains regarding the origin, diversification, and expansion of Tibeto-Burman populations. In this study, we analyzed a 7.0M bp region of 285 Y-chromosome sequences, including 81 newly reported ones, from male samples from Tibeto-Burman populations and other related Eastern Asian populations. We identified several paternal lineages specific to Tibeto-Burman populations, and most of these lineages emerged between 6000 and 2500 years ago. A phylogenetic tree and lineage dating both support the hypothesis that the establishment of Tibeto-Burman ancestral groups was triggered by Neolithic expansions from the middle Yellow River Basin and admixtures with local populations on the Tibetan Plateau who survived the Paleolithic Age. Furthermore, according to the geographical distributions of the haplogroups, we propose that there are two Neolithic expansion origins for all modern Tibeto-Burman populations. Our research provides a clear scenario about the sources, admixture process and later diffusion process of the ancestor population of all Tibeto-Burman populations.