АвторТема: MtDNA control region variation affirms diversity and deep sub-structure in popul  (Прочитано 1060 раз)

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MtDNA control region variation affirms diversity and deep sub-structure in populations from Southern Africa // BMC Evolutionary Biology 2013, 13:56 doi:10.1186/1471-2148-13-56, Published: 27 February 2013

Carina M Schlebusch, Marlize Lombard and Himla Soodyall

The current San and Khoe populations are remnant groups of a much larger and widely dispersed population of hunter-gatherers and pastoralists, who had exclusive occupation of southern Africa before the influx of Bantu-speakers from 2 ka (ka = kilo annum [thousand years] old/ago) and sea-borne immigrants within the last 350 years. Here we use mitochondrial DNA (mtDNA) to examine the population structure of various San and Khoe groups, including seven different Khoe-San groups (Ju/'hoansi, !Xun, /Gui+//Gana, Khwe, =Khomani, Nama and Karretjie People), three different Coloured groups and seven other comparative groups. MtDNA hyper variable segments I and II (HVS I and HVS II) together with selected mtDNA coding region SNPs were used to assign 538 individuals to 18 haplogroups encompassing 245 unique haplotypes. Data were further analyzed to assess haplogroup histories and the genetic affinities of the various San, Khoe and Coloured populations. Where possible, we tentatively contextualize the genetic trends through time against key trends known from the archaeological record.

http://www.biomedcentral.com/1471-2148/13/56/abstract

 

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