АвторТема: Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees.  (Прочитано 1365 раз)

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Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees.
Nunez C, Sosa C, Baeta M, Geppert M, Turnbough M, Phillips N, Casalod Y, Bolea M, Roby R, Budowle B, Martínez-Jarreta B.
Source

Carolina Nunez, Department of Forensic Medicine Faculty of Medicine C/ Domingo Miral S/N, Zaragoza 50009, Spain, carolina@unizar.es.


Abstract

Aim. To perform a genetic characterization of 7 skeletons from medieval age found in a burial site in the Aragonese Pyrenees. Methods. Allele frequencies of autosomal short tandem repeats (STR) loci were determined by 3 different STR systems. Mitochondrial DNA (mtDNA) and Y-chromosome haplogroups were determined by sequencing of the hypervariable segment 1 of mtDNA and typing of phylogenetic Y chromosome single nucleotide polymorphisms (Y-SNP) markers, respectively. Possible familial relationships were also investigated. Results. Complete or partial STR profiles were obtained in 3 of the 7 samples. Mitochondrial DNA haplogroup was determined in 6 samples, with 5 of them corresponding to the haplogroup H and 1 to the haplogroup U5a. Y-chromosome haplogroup was determined in 2 samples, corresponding to the haplogroup R. In one of them, the sub-branch R1b1b2 was determined. mtDNA sequences indicated that some of the individuals could be maternally related, while STR profiles indicated no direct family relationships. Conclusions. Despite the antiquity of the samples and great difficulty that genetic analyses entail, the combined use of autosomal STR markers, Y-chromosome informative SNPs, and mtDNA sequences allowed us to genotype a group of skeletons from the medieval age.


http://www.ncbi.nlm.nih.gov/pubmed/21674829

Рецензия статьи на испанском (речь идет о представителях первой королевской династии Арагона)

http://www.elperiodicodearagon.com/noticias/noticia.asp?pkid=681716

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