https://www.nature.com/articles/s41431-019-0496-0Open Access
Published: 05 September 2019
The Dutch Y-chromosomal landscape
Eveline Altena, Risha Smeding, Kristiaan J. van der Gaag, Maarten H. D. Larmuseau, Ronny Decorte, Oscar Lao, Manfred Kayser, Thirsa Kraaijenbrink & Peter de Knijff
European Journal of Human Genetics (2019)
Abstract
Previous studies indicated existing, albeit limited, genetic-geographic population substructure in the Dutch population based on genome-wide data and a lack of this for mitochondrial SNP based data. Despite the aforementioned studies, Y-chromosomal SNP data from the Netherlands remain scarce and do not cover the territory of the Netherlands well enough to allow a reliable investigation of genetic-geographic population substructure. Here we provide the first substantial dataset of detailed spatial Y-chromosomal haplogroup information in 2085 males collected across the Netherlands and supplemented with previously published data from northern Belgium. We found Y-chromosomal evidence for genetic–geographic population substructure, and several Y-haplogroups demonstrating significant clinal frequency distributions in different directions. By means of prediction surface maps we could visualize (complex) distribution patterns of individual Y-haplogroups in detail. These results highlight the value of a micro-geographic approach and are of great use for forensic and epidemiological investigations and our understanding of the Dutch population history. Moreover, the previously noted absence of genetic-geographic population substructure in the Netherlands based on mitochondrial DNA in contrast to our Y-chromosome results, hints at different population histories for women and men in the Netherlands.
Тема: The Dutch Y-chromosomal landscape - ландшафт Y-хромосом у голландцев (Прочитано 765 раз)